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    • July 21, 2013 3:12 AM PDT
    • Leading scientist speaks about Boresha



      http://www.youtube.com/watch?v=FzU2S0Frd1M&feature=youtu.be

       

      I am here with world renowned scientist and clinical researcher, Dr. Ann de Wees Allen, regarding her incredible breakthroughs and advancements in food science technology.  Also joining us today is the president of Human Sports Performance and is a specialist in exercise physiology and a long time strength and conditioning coach in professional sports:  Mr. Jeff Krushell.

      They will be discussing how Boresha's B-Skinny coffee and Nuvogene Tea are the only products of their kind and were designed to be the first line of defense to battle the ever growing challenge of obesity and diabetes.

      Details & Purchasing:  http://ph.BFreeSystem.com

       

      Transcript:

      Answering questions -- World renowned scientist and clinical researcher:  Dr. Ann de Wees Allen
      (regarding her incredible breakthroughs and advancements in food science technology)

      Also joining us -- the president of Human Sports Performance and a specialist in exercise physiology and a long time strength and conditioning coach in professional sports:  Mr. Jeff Krushell

      They will be discussing how Boresha's B-Skinny coffee and Nuvogene Tea are the only products of their kind and were designed to be the first line of defense to battle the ever growing challenge of  obesity and diabetes.


      Mr. Jeff Krushell:  I've read some research -- May 17, 2012:  Coffee Drinkers live longer

      Dr. Ann de Wees Allen:  Isn't that incredible?  I'm happy to hear that because I love to drink coffee.

      Mr. Jeff Krushell:  For sure, and there are a lot of other benefits to drinking coffee as well that people might not be familiar with

      Dr. Ann de Wees Allen:  Absolutely!  Harvard medical school stated:  drinking 3 or more cups of coffee a day can reduce the risk of ovarian cancer by over 20%!  That's a large percent!

      Mr. Jeff Krushell:  You know, you look at the research.  It is interesting because it is not the caffeine in coffee that is the miraculous molecule; it is other things.  And it turns out that it is not necessarily the caffeine that is the benefit in coffee!

      Dr. Ann de Wees Allen:  Absolutely!  It turns out it is actually the polyphenols in the coffee and those polyphenols are now being studied by NIH; and hundreds of other clinical researchers are trying to determine which exact Polyphenols in coffee are causing benefits.

      Mr. Jeff Krushell:  So it turns out that coffee has some amazing benefits for health; and according to the study, they can help you live longer (which is great news).

      Dr. Ann de Wees Allen:  And reduce risk of certain types of cancers.  And now researchers are looking at those polyphenols to determine which of those specifically are causing the reduction of those incidence of cancers, and are causing life to be extended.  We're not really sure because there are hundreds of polyphenols and now researchers like myself are trying to isolate them; and what is really interesting is, it turns out how you make the coffee and brew the coffee, and how you produce the coffee bean.  If you damage those coffee beans, you don't get the benefits of the polyphenols.  But if you do infrared roasting, you don't damage the coffee and the polyphenols; and you get the benefits of those, which is extended life span and in some cases is reduced incidences of some cancers.

      Mr. Jeff Krushell:  So not all coffee is equal, that's what people have to understand.

      Dr. Ann de Wees Allen:  You are exactly right.

      Mr. Jeff Krushell:  There is also a dark side to coffee of course.  We have seen links to different issues in metabolism, obesity for example

      Dr. Ann de Wees Allen:  YA, that's the crazy thing about coffee the benefits to coffee have been clearly demonstrated in thousands of clinical trials that are unrelated to weight gain and glucose homeostasis (blood glucose) the health benefits of coffee are found, but the only drawback to coffee is the triggering of weight gain, increased belly fat, and blood glucose imbalances.

      Mr. Jeff Krushell:  Hey doc, listen, people have linked weight gain in coffee to the creamers and sweeteners and all the stuff they're putting into the coffee, but that's not necessarily the truth

      Dr. Ann de Wees Allen:  Not at all!  Clinical researchers including myself have clearly identified the bio-chemical culprits in coffee that trigger weight gain.  The culprits are the disruptions in glucose metabolism, which impair blood glucose homeostasis, and that is caused by just drinking black coffee.  Researchers have clearly identified the bio-chemical culprits in coffee that trigger weight gain.  These disruptions trigger fat storage hormones!

      Mr. Jeff Krushell:  So it is confusing that we are getting studies saying that coffee can help you live longer, but coffee can have some metabolic issues as well.

      Dr. Ann de Wees Allen:  Absolutely!  In fact, there is a famous Hollywood starlet who gained 45 pounds from drinking coffee when her nutritionist was wise enough to say "give up coffee" she lost the 45 pounds and regained her girlish figure after swearing off coffee.  But really, who wants to swear off coffee?  I love coffee!

      Mr. Jeff Krushell:  And it does have its benefits for sure!  We're saying black coffee can have some issues.  We know that the additives (the creamers and the sweeteners that we put in coffee) are also causing problems.  So, is the issue:  maybe we have to fix coffee?

      Dr. Ann de Wees Allen:  You are totally right.  You know, in a large study, coffee was shown to increase the consumption of fattening and fatty foods!  So, one of the things that coffee does is cause reactive hypoglycemic properties and that triggers uncontrollable cravings for doughnuts.  Hey!  Guess why doughnuts and coffee go together!  When you drink coffee, it has been chronically proven that it causes you to crave these high fattening foods like doughnuts.  And these findings are totally consistent with published clinical trials showing that glucose metabolism, which is key in weight gain and diabetes, is impaired shortly after drinking brewed coffee, brown coffee, or even instant coffee!

      Mr. Jeff Krushell:  So, what we see as researchers are saying that drinking plain black coffee can cause cravings for snack type foods and fattening foods but it also is associated with the storage of belly fat!

      Dr. Ann de Wees Allen:  Isn't that crazy?

      Mr. Jeff Krushell:  Totally crazy!

      Dr. Ann de Wees Allen:  Who would have thought that black coffee could wreak such havoc?  Drinking regular coffee causes secretion of certain hormones.  OK?  And Emery University school of medicine stated:  There is something about fat cells in the body the way they respond to hormones.  People with high levels of certain hormones have a tendency to store fat in their bellies.  Well, guess what?  Coffee stimulates those hormones!  It has already been shown by the American Diabetes Association and in the American Journal of Clinical Nutrition!  Two premiere sources of the research saying that coffee imbalances blood glucose.  When you imbalance blood glucose, you gain weight even to the point of obesity and it increases risk of type 2 diabetes; and that is where the craving of snack foods comes in.  When you get low blood sugar (hypoglycemia), you start craving the candy bars and the sodas and the potato chips and French fries and things like that in almost an uncontrollable way.

      Mr. Jeff Krushell:  Well, it is fun to eat those kinds of foods!  no question about it!  In order to offset the obesity epidemic, which is what we are trying to do, and to get people tools:  Where can we go?  What can we do?

      Dr. Ann de Wees Allen:  Well, the issue is, since coffee has so many health benefits, the only obstacle to enjoying coffee has been its propensity to add body fat and weight gain, and disrupt your blood glucose levels!  The solution is to create coffee, basically to reengineer the coffee, in a natural method, that contains an anti-glucose matrix!

      Mr. Jeff Krushell:  So, an anti-glucose matrix:  What does that consist of, for people who may not know what that is?

      Dr. Ann de Wees Allen:  Well, an anti-glucose matrix, and in this case I am calling it buffered caffeine, and, as you know, I received the first patent ever awarded in buffered caffeine that's added to coffee.  That addresses key areas in fat burning metabolism.  So, in order to combat stress-related eating and false food cravings in the drinking of coffee, the body requires the exact opposite of glucose elevation.  So you don't want your blood glucose levels to go up.  What you want them to do is stay balanced and in order to do that you have to put an anti-glucose matrix in the coffee that allows the coffee to balance your blood glucose levels and not to simulate those fat storing hormones!

      Mr. Jeff Krushell:  So we have the problem with glucose and glucose storing and fat storing with coffee, wouldn't that research have to be done by somebody who truly understands the glycemic index, glycemic researchers?

      Dr. Ann de Wees Allen:  Yes indeed.  And that is right up my alley.  As you know, I have been chief of biomedical research at the Glycemic Reserach Institute for almost 30 years, and I am the first person ever to receive a glycemic patent worldwide, and I am the first person ever to receive a patent on buffering caffeine in coffee and tea.  The importance of understanding the glycemic index is if you don't know what stimulates blood glucose, and makes you fat and increases risk of diabetes, you don't know how to fix it.  Why is this important?  Because coffee causes fat storage by stimulating hormones.  If you don't know how to undo it, you can't fix the fat storage problems.  The only way to fix coffee so it doesn't stimulate fat storage is to incorporate the glycemic index into the equation and to use buffered caffeine instead of regular caffeine.

      Mr. Jeff Krushell:  See, I like this because we are not going on about how to change habits or change a culture.  what we're trying to do is give people the tools they can use to win the battle against obesity and this is just one of the great products that is in the Boresha line:  the B-Skinny coffee

      Dr. Ann de Wees Allen:  Given the fact that coffee is the most widely consumed beverage Worldwide and 70-80% of the human population drinks it, and by the way the country that drinks the most coffee is the United States (we've taken that award home); but since coffee has proved to be fattening, increased risk of type two diabetes, we've got to create coffee that doesn't stimulate hormones that stimulate belly fat.  You know, scientists found that drinking only 2 cups of coffee a day triggers the storage of belly fat!

      Mr. Jeff Krushell:  And that has to do with the glycemic index?

      Dr. Ann de Wees Allen:  Absolutely!  The problems associated with drinking coffee all revolve around the glycemic excursions that are caused by ingesting coffee.  Elevation of blood glucose has to do with the glycemic index!  Insulin, which is stimulated, has to do with the glycemic index!  And triggering fat storage in humans with cortisol LPL has to do with the glycemic index!  So, the only way to resolve a glycemic related issue is to bring glycemic experts into the equation to restructure coffee while maintaining its natural profile!  How can we control the obesity epidemic if the most widely consumed beverage in the world causes weight gain?

      Mr. Jeff Krushell:  It seems like a losing battle and, for all intents and purposes, you look at the stats on obesity and overweight

      Dr. Ann de Wees Allen:  YA, we’re losing the obesity battle

      Mr. Jeff Krushell:  There is no question that coffee has a lot to do with that (you mentioned that being the number one consumed beverage on the planet, and certainly here in the US) But, how do we formulate a coffee that’s going to help us negate the issues that we’re seeing by drinking the beverage?

      Dr. Ann de Wees Allen:  Great question!  Well, one of the things that you want to be able to do is to create a coffee that can actually decrease the fat cell size.  Let us remember that the Food & Drug Administration and the Federal Trade Commission are the strongest legal authorities in the United States on claims.  And we’ve been doing caffeine and coffee research from 1983 until 2012.  In order to make claims on coffee that has been reengineered, we had to produce over 700,000 pages of clinical documentation to make the claims on fat-burning coffee.

      Mr. Jeff Krushell:  That product is Boresha’s B-Skinny coffee.

      Dr. Ann de Wees Allen:  Absolutely! The claims that we are legally allowed to make include:
      •decreasing fat-cell size (now, that is not an easy one!  We had to do biopsies of fat cells and show that they were shrinking).
      •promotes fat breakdown (that’s a very difficult claim to get)
      •boosting metabolism (of course, why do people drink coffee)

      Mr. Jeff Krushell:  To get energy of course, and that is one of the reasons it is the most consumed beverages on the planet.

      Dr. Ann de Wees Allen:  Right!  And if you can take the coffee and increase the metabolism -- which means increasing energy levels and postponing fatigue -- you can reengineer coffee to be a metabolic booster (to provide the same energy the coffee gives you without the negative downsides).  And in order to increase metabolism, you have to make a beverage (in this case, coffee) thermogenic!  Now, if you don’t increase thermogenisis in the right way:  you Increase appetite, you make it kenogenic, and you produce all kind of negative status in the body which we don’t want to do.  So, the low glycemic matrix (which is the buffered caffeine) actually decreases fat-cell size, boosts metabolism, promotes fat break-down, and gives you better long-term energy without exhausting your adrenal gland!

      Mr. Jeff Krushell:  What is one of the things we see, doc:  the adrenal fatigue in coffee drinkers (that mid-day crash, so to speak)?  We see it all the time!

      Dr. Ann de Wees Allen:  And also we see it in any kind of energy drink that contains caffeine.

      Mr. Jeff Krushell:  How about some of these drinks out there that contains three to four times the amount of caffeine that a regular cup would have?

      Dr. Ann de Wees Allen:  That is so crazy!  It makes me crazy!  Really, the human body is not meant to ingest more than 100 – 120 mg of caffeine at one time.  That is just crazy!

      Mr. Jeff Krushell:  Well, how about let’s talk about this:  you mentioned thermogenesis.  Now, thermogenesis we talked about as being the first line of defense against weight gain, obesity, and type 2 diabetes.  This is something that is very exclusive and very special in the Boresha product line and certainly for the B-Skinny coffee.

      Dr. Ann de Wees Allen:  Right!  And the solution is to create a coffee that is effective at Increasing energy, and acting thermogenesis and outapose tissue fat-burning; and the way that you do that is to turn on fat thermogenesis in humans which is called DIT (diet induced thermogenesis):  The primary mechanism in the human body for excess energy removal.  Scientists call it excess energy removal, but it really means eating excess food or gaining too much weight.  The primary mechanism in the human body for dealing with that is called thermogenesis:  energy removal.  Now, what is that?  The body has to remove or burn, to utilize, calories and nutrition that we eat.  When we ingest more than we can use, we store that excess energy in the fat cell.  Those are little pods of stored excess energy.  Only those little pods soon grow into large pods, and then they create more storage pods until our bellies are full of storage pods and we don’t look so slim anymore.  Ever see a large belly hanging over a belt?  That’s not a pretty sight!  So, the smart override system in humans to get rid of that fat is called thermogenesis – fat burning thermogenesis.  And it is a first line of defense against weight gain, obesity, and diabetes.

      Mr. Jeff Krushell:  But as we get older, doc, the thermogenic process slows down.  Our whole metabolism slows down and the fight gets harder and harder.

      Dr. Ann de Wees Allen:  YA, I hate when that happens.  As we get older, or even as we gain excess weight, thermogenic fat-burning slows down.  You know, if you look at the research, people that are obese have very slow thermogenesis.  Age related lowering hormones greatly effects this slowing-down process.  Estrogen is a fat-burning hormone; so, women, after they go through menopause – they start gaining weight.  Growth hormone and testosterone are powerful thermogenic fat-burning hormones; and we start losing those at age 23.  So, hormones that instigate thermogenesis start to slow down as we get older, but they also start to become inactive when we gain excess weight, and then we need to stimulate thermogenesis.

      Mr. Jeff Krushell:  So, one of the answers here would certainly be exercise – moderate exercise – everybody do what they can, but on the other side, there are other ways in initiate or instigate thermogenesis.  So, as we age, the hormones essentially make us fatter.

      Dr. Ann de Wees Allen:  Yes, because nature wants us to be fat!  And as we age, these hormones diminish to very low levels, and that increases fat storage instead of fat burning.  Not good!  When the body is fed the right fuel combined with exercise, you don’t gain excess body fat until after age 30.  Children and teenagers have thriving hormone levels which keeps them lean unless there is excess energy taken in.  So, after age 30, thermogenesis slows way down and it only gets worse as age progresses.  Remember the growth hormone:  the main youth hormone starts diminishing at age 23!  And age 23 is technically when aging begins.  I hate when that happens. Don’t you?

      Mr. Jeff Krushell:  So we have a spiral effect here.  We’re losing our energy.  We are gaining weight.  Our hormones are causing problems.  And we are drinking coffee to give us energy to offset the problem, but coffee is causing the problem – so we have a whole myriad of issues here, but we kind of solved it with the B-Skinny Coffee.

      Dr. Ann de Wees Allen:  YA!  That’s a perfect way to put it!  The way you just put it is great!  In obese people, GH levels are really low!  And when GH Growth Hormone levels are normal, internal fat burning is very effective.  So, internal thermogenic fat-burning is based on hormones, genetics and body type.  But internal fat-burning thermogenesis is not the only game in town.  There is external thermogenesis which is called DIT:  Dietary Induced Thermogenesis.  And that is a major player in getting rid of excess body fat.  Imagine if we can reinstate internal thermogenesis as we age and also trigger DIT fat-burning thermogenesis.

      Mr. Jeff Krushell:  Well, that would be very cool, and effective at attacking excess body fat that people are carrying around.

      Dr. Ann de Wees Allen:  YA!  And it is actually easy to do!  It sounds complicated, but it is not if you know how to do it; and we know how to do it right.  And we also know how to do it safely because that’s the most important aspect.  I know how to do it because I have been studying it for almost 30 years and I received a federal patent in the mechanism for creating thermogenic fat burning in humans.  You know, the crazy thing about ingesting energy is that your body does not care if there are calories in a food or drink or even if it contains any sugar whatsoever.  It can still make you fat.

      Mr. Jeff Krushell:  And this is kind of the premise of the diet soda studies that went on saying that even no calorie or low calorie / low fat can still cause fat storage.

      Dr. Ann de Wees Allen:  Isn’t that nuts?

      Mr. Jeff Krushell:  It’s crazy!

      Dr. Ann de Wees Allen:  It is actually called the cephalic response and that stands for CPIR:  Cephalin Phased Insulin Response.  But it is responsible for why diet sodas had been tagged as fattening.  Hey, what if you can design  low glycemic and non-cephalic foods and beverages including coffee.  Wouldn’t that solve the problem?  Indeed it would!

      Mr. Jeff Krushell:  Problem solved!  Boresha’s B-Skinny coffee!
      Now let me ask you this:  What about people who don’t particularly like coffee or drink coffee?

      Dr. Ann de Wees Allen:  Well, the third most commonly ingested drink in the world – water being number one, coffee being the most consumed beverage, and then there is tea!  So, if you are going to make everybody happy, you have to make a tea that is thermogenic and not just a coffee.

      Mr. Jeff Krushell:  So, tell us more about the tea.

      Dr. Ann de Wees Allen:  Well, I created Nuvogene Tea; which is a patented, safe, and very efficacious product designed for weight management, excess body-fat, stress eating, and hunger control; because I know that myself and my sisters who were stuffing popcorn in our faces are thinking about hunger control, which we do not have!

      Mr. Jeff Krushell:  That does not come easy.  Let’s face it!  We talked kind of jokingly, in light of all the research that went into this product, but you worked with some of the top genetic researchers Johns Hopkins and NIH to put this together and that’s pretty special.

      Dr. Ann de Wees Allen:  Absolutely!  If you don’t take genetics into account, you’re not going to be able to create a very effective product.  Let’s face it, genes rule!  If we could control genes:  I’d be taller, I’d wear a smaller shoe size, you'd be 7’3” and playing basketball.  OK?  So, we don’t get to control genes, per se.  But we can control how they act!  We can put bad genes, which are called polymorphisms , on a dimmer switch.  And the tea actually contains a dimmer switch for the obesity gene.  The FTO Obesity gene is the strongest known common genetic risk for obesity! And guess what, about half of the people in the United States have that gene!

      Mr. Jeff Krushell:  So we have that gene:  the FTO Obesity gene.  What you’re saying is:  It is there, you can’t change your genetics, let’s face that!
      Dr. Ann de Wees Allen:  (Right!)
      Mr. Jeff Krushell:  That’s a good point.
      Dr. Ann de Wees Allen:  (Right!)
      Mr. Jeff Krushell:  But what you’re saying is, we can kind of put them on a dimmer switch and maybe almost turn them off.

      Dr. Ann de Wees Allen:  You are exactly right!  I’ll give you a good example.  If someone has lung cancer running in their family and there are genes like the BRCA genes that greatly increase your risk of ovarian and breast cancers. And there are very aggressive treatments for those types of genes (for the BRCA genes and other kinds of genes of that nature).  If you have the genetic propensity, the polymorphism for some types of diseases (lung cancer, breast cancer, ovarian cancer) then your physician generally recommends very aggressive treatment.  But what do you do if you have the obesity gene, which almost 50% of the population has, and you don’t even know it?  If you look at sisters in one family, the FTO Obesity gene can jump around in brothers too.  So you can look at five kids in a family and three are thin and two are obese or greatly over weight.  Well, it is likely that those two eat the same foods as the other siblings, but they gain weight.  Have you ever looked at someone who can eat like a pig – 10,000 calories a day – and they don’t gain any weight; versus someone that is in their family that eats a lettuce leaf and it turns to fat!

      Mr. Jeff Krushell:  Well, I have seen it in my family.  Everybody eats very well, but just the way some of the people store that energy as opposed to other people.  It is crazy the differences; and that, potentially, is the FTO Obesity gene in action!

      Dr. Ann de Wees Allen:  Right!  And everybody cannot just march into a research center and say excuse me, please tell me if I have the FTO Obesity gene.  It is not covered by insurance, it is kind of hard to figure out.  So, what I decided to do was to put a down regulator of the FTO Obesity gene, because it  is so prevalent in people, into the Nuvogene tea; and now the Nuvogene tea is the only non-drug product that addresses genetic risk factors for obesity in humans.  So, the coffee gives you energy and causes thermogenesis, and then the tea addresses the FTO Obesity gene and also gives you energy and thermogenesis.

      Mr. Jeff Krushell:  So it is a double whammy!  You can’t lose with either of the products; and for people who don’t particularly like coffee, the NuvoGene tea is a great option.

      Dr. Ann de Wees Allen:  You know, what I like to do is to have the B-Skinny Coffee in the morning, and then be a naughty girl and probably eat something for lunch that I shouldn’t eat, and then (to help compensate for that) between lunch and dinner I am going to drink a NuvoGene tea.  The reason being is that the tea instigates thermogenic fat burning – it speeds up fat burning inside the fat cell, it gives you maximum natural energy, it gives me hunger management, stress eating control, anti-glucose matrix, and it helps beat the FTO Obesity gene.  That makes me happy.

      Mr. Jeff Krushell:  Absolutely!  So we are looking at coffee – and there are those special compounds you mentioned in coffee that potentially, according to the latest research, can help people live longer; but inside tea as well there are also special compounds that have been associated with general health.  Yes, they’ve been isolated and they are actually very different from the coffee polyphenols.  So, scientists like myself are trying to isolate those coffee polyphenols in coffee.

      Dr. Ann de Wees Allen:  So it is quite clear we are losing the war against obesity and diabetes.  Why?  Because we are not addressing the cause.

      Mr. Jeff Krushell:  We know that adipose tissue is not passive at all.

      Dr. Ann de Wees Allen:  I know, and that was really shocking to researchers because, for as long as we have been doing research on this planet, we understood that fat was passive.  It just sits there.  It is a passive fuel dump.  OK?  We eat food, it goes into the dump, it is a passive fuel dump.  But, alas, it turned out not to be true.  It turns out – from very, very current research – that adipose tissue fat (or fat cells) are robust tissues that release hormones and other chemicals that tell us to get more fat.  

      Mr. Jeff Krushell:  Fat is active and that is contrary to common belief (without question).  What are we going to do about it?  Knowing that fat cells are not passive, they are active living organisms potentially looking to get fatter.

      Dr. Ann de Wees Allen:  They want to get fatter.

      Mr. Jeff Krushell:  They want to get fatter.

      Dr. Ann de Wees Allen:  They love getting fat.

      Mr. Jeff Krushell:  What do we do about it?

      Dr. Ann de Wees Allen:  Well, you got to fight back.  So far, what we’ve been doing is not working.  It is very clear on that.  Childhood obesity, adult obesity and diabetes are completely out of control; and nothing that we’ve been able to do has slowed it down in the slightest way; and now it is spreading to other countries.  What we have to do is fight back with techniques that actually attack the fat cells and attack the metabolism that causes the fat cells to get big, bigger and bigger.  The most aggressive thing we can do — the number one line of defense against that obesity and weight gain is to stimulate thermogenesis three times a day; because foods and beverages are stored in white fat cells that pile up in the body.  They love to pile up in the thighs and abdomen.  Brown fat cells help those fat cells get rid of excess fat. So, if we can stimulate the brown fat cells to be aggressive (to move the fat out of the fat cells) that is thermogenesis.  Brown fat cells help those fat cells get rid of excess fat.  What we, as scientists, do is to try and trigger those fat cells into thermogenesis and burning the fat faster.

      Mr. Jeff Krushell:  Excellent!  So you mentioned — three times a day — this is where Boresha products can really be functional.  Three times a day — taking the tea or coffee, working it into your daily plan; because we know that as we age thermogenesis slows down.  If we are not doing something proactive to stimulate thermogenesis, those fat cells are going to win that war.

      Dr. Ann de Wees Allen:  We are going to get fatter as we get older, and I also hate when that happens.

      Mr. Jeff Krushell:  These products can potentially be called the first line of defense in this war against obesity.

      Dr. Ann de Wees Allen:  You are exactly right.  That is the way I look at the Boresha coffee and tea — the Nuvogene tea and the B-Skinny coffee.  That is your first line of defense against weight gain, obesity, and diabetes; because, remember, the same thing that is causing the obesity epidemic is causing the diabetes epidemic.  Is there any coincidence that those two things are linked?  No, because what causes them:  constant ingestion in humans of high glycemic foods that stimulate blood glucose and insulin levels.  If you keep stimulating your blood glucose levels and your insulin levels day after day, hour after hour, with food and beverages, then what you do is coerce your fat cells into getting bigger and bigger and bigger.  Just before they implode — they start subdividing like lemmings, and making more and more fat cells to make a bigger hotel so that there can be more pods filling up.

      Mr. Jeff Krushell:  And once you have those fat cells, you have them!

      Dr. Ann de Wees Allen:  You got it!  They are not going!  You think you can suck those little babies out.  You can’t!  There is only a certain type of adipose tissue you can suck out of the body.  So, it is not effective to try to use liposuction to try to get those type of  fat cells out of the body.  What can we do?  First of all, we can stimulate thermogenesis three times a day cause that is the magic number; three times a day, in between meals.  You don’t want to confuse the body by saying “I am going to eat this meal and at the same time I am going to induce thermogenesis” because that means the push-me — pull-me (you want to give me food and you want me to use this food to build my body but then you want me to burn this food).  That is too complicated!  That is why you do thermogenesis in between meals; because you don’t want to complicate the body.  What you can do is have the coffee in the morning and then you can have ice coffee (two times) in between meals, or you can have the regular B-Skinny coffee hot in the morning, which is what I do, and then have the tea in between breakfast and lunch, and then I have the Nuvogene tea again in between lunch and dinner.  Here is a great tip, ladies: sometimes we really go into dinner with a very big appetite (it is like me and my sisters:  we eat everything on the table — which is fried chicken, mashed potatoes, and creamed corn — not a good thing to eat — two of those things are high glycemic).  What we want to do is, a half an hour before we are going to eat a meal that you know darn well that you are going to overeat, cause you are starving…  and here is why you are starving:  you start eating food and it takes 25 minutes before your brain knows  you have had anything to eat.  How much food do you think you can eat in 25 minutes?

      Mr. Jeff Krushell:  I can pack in a lot of food in 25 minutes.

      Dr. Ann de Wees Allen:  Who is going to sit there, really, before you eat something, and wait 25 minutes for your brain to go:  AH HA!  I’m full!  It does not work that way!  So, if you drink the tea a half an hour before you are going to eat a meal, it blunts those food cravings that are produced.

      Mr. Jeff Krushell:  So the first line of defense obesity and overweight is to take the Nuvogene tea and the (B-Skinny) coffee three times a day.  What else can we do?

      Dr. Ann de Wees Allen:  Right.  The second most important thing we can do is to eat food and beverages that don’t stimulate fat storage (which is low glycemic foods and beverages).

      Mr. Jeff Krushell:  Anything else?  I know we have talked about the benefits of the coffee.  We’ve talked about the benefits of the tea.  We know about thermogenesis.  Eat low glycemic foods and beverages.
          
      Dr. Ann de Wees Allen:  The third most important thing is:  don’t stimulate the cephalic response, which is called brain glycemic indexing.  Don’t stimulate insulin because insulin stimulates LPL — that little gate keeper of fat storage in the fat cell.  If you look at how insulin is stimulated,  it is by eating high glycemic foods and drinking high glycemic beverages.  But there is another more-sneaky way that insulin levels are exacerbated.  That is by drinking diet sodas, or drinks that have no calories and no carbohydrates (but they have artificial sweeteners in them, which stimulate ten times more insulin).

      Mr. Jeff Krushell:  So how is that possible?  This is going to trick a lot of people.  No calories — no carbohydrates — equals weight gain.  Very confusing!

      Dr. Ann de Wees Allen:  Absolutely!  When people come into our laboratory and they say they have a great diet program that they have been on and they can’t understand when they are fat.  Alright!  So, we sit down and the first thing we do when we take their blood levels and look at their blood glucose and insulin levels and any genetic risk factors, we are going to look at what they eat and drink.  Now, the ones that say “I am on a perfect diet!  I am on a perfect program!  And yet I gain 25 pounds”, how is that working for you?  Well, that is not working for you.  It is very easy to explain to them:  let’s see.  You had four diet sodas.  You had foods that said:  No sugar, No calories, No carbohydrates, and you have basically ingested these foods all day long.  Is that right?  And they say:  Yes, indeed, so why am I gaining weight?  That’s why you are gaining weight.  Foods and beverages that don’t contain any calories and carbohydrates have to contain something.  They are not made of air.  Unless they are eating Styrofoam, there is something in that food!  Well, the something that is in that food is basically ingredients that cause you to stimulate insulin.  So if a product says zero calories, zero carbohydrates, zero sugars; what is in there?  It is not Styrofoam and it is not air.  It is artificial sweeteners.  Now, artificial sweeteners tell the brain that something is coming into the body that is 600-1000 times sweeter than sugar (regular sugar or honey), and so what the brain does is respond by pumping out insulin, and that triggers fat storage.

      Mr. Jeff Krushell:  Red alert!  Red alert!  It is coming down the pipeline!

      Dr. Ann de Wees Allen:  Absolutely!  And it doesn’t matter if you just swish the diet soda around in your mouth and you spit it out.  It doesn’t even matter if you swallow it because it is the receptors on the back of the tongue that will tell the brain if that product has perceived calories — there’s real calories.  If I eat a hot fudge sundae and you eat it with me, those are real calories.  That is not made up in our heads.  That is not perceived!  It is real!

      Mr. Jeff Krushell:  That information alone can change people’s lives!

      Dr. Ann de Wees Allen:  It is going to have to; because if you watch the 60-minutes Sanjay Gupta series that was on recently, then on Katie Couric, scientists are busting with the information and trying to get the information out to the world that the cephalic response of foods with just brain glycemic indexing, and that is what they are calling food addictions, is causing the obesity epidemic just as much as overeating high glycemic foods.

      Mr. Jeff Krushell:  So, people are eating these foods that they think are diet foods — healthy for them, no calories — but it is actually working the opposite way; which, again, as we heard several times tonight, goes against common thinking.

      Dr. Ann de Wees Allen:  But you know what?  The obesity epidemic and the diabetes epidemic is not based on logic.  It is based on anthropology.  So we have to stop looking at what we think is logical and look at how the human body actually gets fat and eventually develops diabetes, and attack those things — which is to stop eating those foods which stimulate blood glucose and insulin.  It is just that simple.  Foods that stimulate blood glucose and insulin are high glycemic foods and high cephalic foods.  You know, there is a very well known ice cream in the grocery store (I won’t mention any brand names).  We’ve tested it.  It says “no sugar”, “this is a great diet food”, “sugar free”, “great food”, “great diet food” — well, guess what, that is more fattening than if you ate 5 bowls of regular ice cream or five fudge bars because the ingredients in that bar stimulate the glycemic and the cephalic response!  Remember, you don’t even have to swallow something  or it to make you fat!  Your body just has to think it is fattening!

      Mr. Jeff Krushell:  Right, so, understanding this is very important as we move forward in the battle against obesity.  We have a couple of things to think about here.
      One:  We have to exercise, no question about it.
      Two:  You’ve talked today about the diets and eating the proper foods.  We’ve talked about thermogenesis and you’ve explained that very well.  We know what a powerful tool that is in the Boresha product line.  We’ve talked about the cephalic response which is a really tricky situation where are brain thinks something is coming in and turns on the fat storing mechanisms.  And we have also talked about the glycemic index which is one of the root sciences that push these products forward.
      So, can you explain the glycemic index and how it works so people can understand how to use it in their daily life?

      Dr. Ann de Wees Allen:  You know, you hear the words “the glycemic index” a lot these days, and when I started the research in 1983 nobody knew what the glycemic index was and they didn’t care what the glycemic index was.  I think I was the only one that was obsessed with it; and I am very happy to note that now the glycemic index is becoming more and more commonplace in the fight against diabetes and obesity; and here is what the glycemic index is:  All foods, drinks, snacks, nutrients, supplements, and anything else that you put into your mouth will elicit a metabolic response, and that includes gum.  Now, we don’t swallow gum, but we chew gum.  As the food goes into the mouth and gets processed, the body has to decide what to do with that ingested item.  So, really, the body has two main pathways to choose from.  You can (pathway number one) store the item in those fat cells — those fat pods — or (number two) you can utilize, or burn, the item as energy.  Humans are genetically hardwired to shunt foods into the fat cells whenever possible.  So, the mechanism by which the two main pathways are accessed depends on the glycemic index and the glycemic load of the item.

      Mr. Jeff Krushell:  So, doc, there are a lot of companies out there that seem to claim glycemic responsible or glycemic friendly foods.  In your  government certified testing lab, how do you go about identifying whether a food is glycemically friendly or high or low or however you rate them?

      Dr. Ann de Wees Allen:  Great question!  What we do is bring in our guinea pigs — I mean, our human subjects — and we test their blood glucose levels and their insulin levels to make sure that they are stabilized (or if they are not then we record what the level is of the blood glucose and insulin levels).  Remember, we have to separate diabetics from non-diabetics because if you give a diabetic (if you feed a diabetic) the same food or beverage that you give a non-diabetic, you will get two completely different responses.  So, if I take a piece of bread and I feed it to a non-diabetic, and I take that same piece of bread and feed it to a diabetic — guess what?  You get a different glycemic index.

      Mr. Jeff Krushell:  So, you are telling me that your laboratory does not rely on analytical analysis through a computer

      Dr. Ann de Wees Allen:  No, that’s illegal!

      Mr. Jeff Krushell:  You are actually using human beings to test their response to foods.

      Dr. Ann de Wees Allen:  You have to!  

      Mr. Jeff Krushell:  Very cool!

      Dr. Ann de Wees Allen:  The food and drug administration and the federal trade commission mandate, which means it is legally mandated that, if you are going to claim a glycemic index on any food or beverage within the United States, you have to have done human embivo clinical trials, which means you got to take a human being, you’ve got to stick them with a needle, and suck some blood out, and you have to quantify it that way.  So what we do is, we will take thirty subjects, non-diabetic and diabetic, and separate them out — because remember, they are going to get different responses.  That’s why we have two different determinations:  one is diabetic friendly, and one is low glycemic.  Low glycemic means it is low glycemic in the average person that is non-diabetic.  Diabetic friendly means it is low glycemic in a diabetic.  So there will be some products that qualify as low glycemic but they don’t qualify as diabetic friendly because remember that 80% of the American public has insulin resistance and metabolic syndrome:  80% as opposed to when I started the research in 1983 when it was 10%.  That just gives you an example of how wacky our body is going.  We are now at 80%, and we are going towards 100% of the population having insulin resistance and metabolic syndrome — which means, if you have insulin resistance and I don’t, I can eat the same food that you do, and you are going to get fatter than I am; because it causes your hormones to go wacky, and it stimulates insulin, which drives food and fat into the fat cells.  So we are going to test their blood glucose, and we are going to fee them a food or a beverage in a very defined amount.  We use FDA CFR 21 guidelines for determining the amount of food.  It is very upsetting to me as a glycemic index researcher to see that some laboratories are using a serving size that can be put in a thimble.  If you put a serving size in a thimble and you say that is low glycemic, I would not say that is validated low glycemic food.  We use the mandated size that the food and drug administration states in CFR 21.  In other words, if the FDA says the serving size is half of a cup, we feed them half of a cup and we don’t let the clients choose what the serving size is (because the data is skewed that way).  That is how a lot of these products are stating to be low glycemic when they are not!  If I give you a thimble full of anything, you are not going to get an appreciable glycemic response.  Then we are going to track them over the next four hours and draw their blood levels to see where is their blood glucose and where is their insulin levels — and from that we can extrapolate how it is going into the fat cells, how fattening that food is, and how much of a risk that food is to a diabetic, or to develop type-2 diabetes.  If a consumed item has a high glycemic index, and a high glycemic load, it will primarily take pathway number one — which is to store the item in the adipose tissue fat cell.  But if a food has a low glycemic index, and a low glycemic load, it takes primarily pathway number two — which means to burn the food as energy.  So, quickly digested and metabolized foods possess the highest glycemic indexes:  like bananas and potatoes and French fries (and maltodextrins, by the way).  Slowly digested foods release glucose gradually into the blood stream, and those are low glycemic.  All foods, drinks, and nutraceuticals are categorized as either high or low glycemic.  High glycemic foods elevate blood glucose and insulate levels and they stimulate fat storage.  Low glycemic foods do not overly elevate blood glucose and insulin and they don’t stimulate fat storing mechanisms.

      Mr. Jeff Krushell:  The Boresha B-Skinny coffee and the Nuvogene tea have all gone through this certification process.

      Dr. Ann de Wees Allen:  Yes, and not only human envivo clinical trials in adults and in diabetics, but in children ages 6 – 18 when it is appropriate to determine how the glycemic index looks in a child, which is very different then how it looks in an adult.  The bottom line is if you don’t know the clinical aspect of a product, and a clinical response whether it is high glycemic or low glycemic, and the cephalic response — you cannot predict if that food is going to make you fat or not fat, and you cannot predict if that food or beverage is going to exacerbate type two diabetes.  So it is very important to define the glycemic index of a food and to define the glycemic load.  Every single product in Boresha International has been clinically designed on the glycemic index and the parameters to stay within the glycemic index and glycemic load and be non-cephalic at the same time.  By the way, Boresha International is the only company in the world where all the products fit into the low glycemic modality and non-cephalic modality (which is brain glycemic indexing).  No other company in the world has that type of a criterion.

      Mr. Jeff Krushell:  That is something that everybody can be proud of, doc.  So we talked about the coffee and we talked about the tea today.  We talked about all the benefits to those products.  Understanding the science is important, there is no question about it; but making them functional and making them easy to use for people in their daily lives is certainly a key.  The glycemic index, very interesting, but there is more to the glycemic index than simply cutting out sweets and sugars.

      Dr. Ann de Wees Allen:  There really is. It is all carbohydrates and all foods that contain anything that elevates your blood glucose or insulin levels.  One of the things we recently tested for was cookies.  There are a lot of companies trying to create low glycemic chocolate chip cookies, and I would personally be thrilled if they could do that cause I do want a good chocolate chip cookie (as do most people) — but flower is high glycemic.  It is totally high glycemic.  Almost anything you mix with flower, it doesn’t matter what sugar or sweetener you mix with it, it is still going to be high glycemic — and that is the problem.  It is very difficult to make brownies or cookies or anything like that is low glycemic because of the flower.  So all carbohydrates, whether they are starchy or sweet, quickly turn into glucose in the blood stream.  A bagel, for example, hikes your blood sugar as much as a doughnut.  So people are thinking “I will just have a nice healthy bagel for lunch with some cream cheese” instead of a doughnut — well, guess what?  That isn’t going to do you any good whatsoever.

      Mr. Jeff Krushell:  Alright.

      Dr. Ann de Wees Allen:  Because a bagel and a doughnut quickly turn into glucose in your blood stream.

      Mr. Jeff Krushell:  What you are saying is, a high glycemic food (regardless of what it is) is going to stimulate fat storage.

      Dr. Ann de Wees Allen:  Absolutely!  In beverages too!  And that’s why high glycemic foods and drinks lead to type two diabetes.  If you think about it, people who have type two diabetes are typically overweight.  But people who have type one diabetes are very thin!  In type one diabetes, people are not producing enough insulin and they become catabolic (so they lose muscle mass).  It is not so much the fat that they lose in a type one diabetic, it is that they have no muscle mass and that becomes very dangerous and potentially life threatening.  When you have pre-diabetes or type two diabetes, either your body does not produce enough insulin or your cells do not use it efficiently, and as a result of that, glucose builds up in the blood.

      Mr. Jeff Krushell:  So, doc, when we look at the most recent research, we see that exercise has an impact on blood sugar.

      Dr. Ann de Wees Allen:  YA, we never used to know that.  Researchers only recently — as recently as 2012 — found out that when you exercise, your body is better able to employ its supply of insulin, which is really decreasing insulin resistance, making it easier to control blood sugar level.  It is crazy that new research is showing that exercise allows your body to use your sugar more effectively so it doesn’t sit in your bloodstream causing end organ damage.  So now we have a good picture of how blood sugar builds up from food and beverages and it also builds up from sitting in front of the television.

      Mr. Jeff Krushell:  So getting out and moving and shaking a little bit is one of the keys in this fight against obesity.

      Dr. Ann de Wees Allen:  Absolutely!  Even walking around the block, as long as you are moving.

      Mr. Jeff Krushell:  Before people get involved in an exercise program, we certainly want them to check with their physician; but everyone should be out there moving.  From the research that you and other scientists have done, what you are showing us is, when we take a sugary drink it increases insulin; also when we consume a drink that has no sugar or no calories we are also seeing fat storage.

      Dr. Ann de Wees Allen:  YA!  Either way!  The data is really strong on this!  Scientists even locked kids in a hospital, fed them sugar, and measured their blood every thirty minutes.  We kind of do that in our laboratory, but not with kids.  It did not take long for things to turn really bad.  Like Sanjay Gupta said on 60-minutes, if you are thinking that diet soft drinks or even artificial or even natural sweeteners are the answer to getting off of sugar, think again!  I am quoting Sanjay Gupta:  “Diet drink consumption has increased 400% since 1960.” Those who consume diet drinks regularly have a 200% risk of weight gain.  Drinking diet drinks regularly causes a 200% increased risk of weight gain, a 36% increased risk of pre-diabetes or metabolic syndrome, and a 67% increased risk of diabetes.  A study of 400 people found that those who drink two diet sodas a day increased their waste size by five times.  Guess what?  You cannot outsmart mother nature!

      Mr. Jeff Krushell:  We’ve been duped!  Not only are people drinking the diet sodas because people think it is going to help them control their weight problems, but I think it also gives people the loose confidence that they can go out and eat other foods that may not be good for you as well.  We get a double whammy.

      Dr. Ann de Wees Allen:  For so many years, we have all been lulled into this false sense of happiness with food that we can drink anything we want as long as it says diet on it and we can eat anything we want as long as it says diet on it, and we are going to get thin.  Well, I certainly think that theory has been proved not to be true.  We are fatter than we have ever been in the history of the world.  We are fatter and fatter and fatter, and remember that we only have two generations to change that before we change our species.  That, frankly, is very scary!  And it occurs in children.  It only takes two generations to change growth height.  You are taller than your fathers. Your sons and your grandsons and your great grandsons will be taller than you are.  That is the way evolution works.  But right now, we only have two generations to change the obesity epidemic or it is going to become a permanent part of our genetics.  That is really scary.

      Mr. Jeff Krushell:  One of the things we have to do in this fight against obesity is to be conscious of what we eat and drink.  Knowing everything we know about the glycemic index and cephalic response, if we take the B-Skinny coffee and, let’s say we add in all those regular sweeteners and creamers and flavor systems, we really destroy the effects of the B-Skinny coffee.

      Dr. Ann de Wees Allen:  You totally and absolutely do.  The purpose of the B-Skinny coffee is to stimulate thermogenic fat-burning and to give you energy, without stripping your adrenal glands.  If you add in the creamers and the sweeteners that are on the market, you will totally destroy the product.  I had to solve that problem.  I created B-Creamy and B-Sweet which are 100% natural low-glycemic creamers and a sweetener that can add to the coffee that works with the coffee and doesn’t work against it and doesn’t block thermogenesis and doesn’t increase risk of type two diabetes.

      Mr. Jeff Krushell:  See, I love it!  You have your black coffee which you can drink black, add the B-Creamy or the B-Sweet if you want a flavor; and if you don’t like coffee, you can drink the NuvoGene tea.  As you mentioned earlier, if you think you are subject to the FTO Obesity gene, you might want to drink the tea a little more often than the coffee.  Doc, we got a great  arsenal of products at Boresha.  Doc, thanks for the conversation tonight.  Great conversation!  Great insights on the product!  It is great to know that no other company has this technology.

      Dr. Ann de Wees Allen:  You’re right!  No other company in the world has the capability of making low glycemic and non-cephalic products.  That is just the tip of the iceberg.  We can make hundreds of products in the future based on this technology.

      Mr. Jeff Krushell:  So, doc, there is literally no competition because this science cannot be duplicated or reverse engineered.  That puts Boresha on the leading edge of food technology.



      Thank you for reading.  For more information about the science and research behind the products, please visit:  http://ph.BFreeSystem.com

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